Pain relief that actually works. Prescribed by doctors. Delivered to your door.
Prescription-strength compounded pain creams — personalized to your condition, shipped monthly. No pills. No opioids. No waiting rooms.
50 million Americans live with chronic pain.
Most are stuck choosing between pills that wreck their stomach and creams that barely work.
There's a better option.
How SoothRx works
Doctor-prescribed pain relief in 3 simple steps
Tell Us About Your Pain
Complete a 5-minute assessment about your pain — location, type, severity, and what you've tried. Our AI analyzes your responses instantly.
Doctor Reviews & Prescribes
A licensed physician reviews your assessment and prescribes a custom-compounded cream formulated for your specific condition.
Delivered Monthly
Your prescription cream ships directly from a licensed pharmacy to your door. Refills are automatic. Adjust or cancel anytime.
Targeted relief for chronic pain
Joint & Arthritis Pain
Knee, hip, shoulder, and hand pain relief with anti-inflammatory + nerve-calming compounds.
Diclofenac · Gabapentin · Lidocaine
Join the Waitlist →Back & Muscle Pain
Lower back tension, muscle spasms, and chronic tightness treated at the source.
Ketoprofen · Baclofen · Cyclobenzaprine
Join the Waitlist →Nerve Pain (Neuropathy)
Diabetic neuropathy, post-surgical nerve pain, and sciatica — without systemic side effects.
Ketamine · Gabapentin · Clonidine
Join the Waitlist →Sports & Recovery
Activity-related pain, overuse injuries, and post-workout soreness — targeted and fast.
Diclofenac · Lidocaine · Menthol
Join the Waitlist →Not another OTC cream.
| OTC Topicals | Oral Pain Meds | Pain Clinic Creams | SoothRx | |
|---|---|---|---|---|
| Prescription-strength | ✗ | ✓ | ✓ | ✓ |
| No pills / no opioids | ✓ | ✗ | ✓ | ✓ |
| Targeted to pain site | ~ | ✗ | ✓ | ✓ |
| Doctor-prescribed | ✗ | ✓ | ✓ | ✓ |
| Delivered to your door | ✗ | ~ | ✗ | ✓ |
| Under $80/month | ✓ | ~ | ✗ | ✓ |
Simple, transparent pricing
Everything included. No hidden fees. Cancel anytime.
Essential
$49 first month
- One compounded pain cream (30-day supply)
- Physician oversight & prescription
- Unlimited messaging with care team
- Free shipping
Complete
$69 first month
- Two compounded creams OR cream + supplement stack
- Physician oversight & prescription
- Unlimited messaging with care team
- Quarterly check-in consultation
- Free shipping
Premium
$99 first month
- Advanced formulation (ketamine-based)
- Standard cream included
- Physician oversight & prescription
- Quarterly video consultation
- Priority shipping
All plans include a 30-day satisfaction guarantee. HSA/FSA eligible. No insurance needed.
What our patients are saying
Join 1,200+ people on the waitlist
“I've been waiting for something like this. I'm tired of taking ibuprofen every day and my doctor says there's nothing else to try.”
Physician-led. Pharmacy-compounded. Delivered with care.
Licensed Physicians
Every prescription is reviewed and approved by a U.S.-licensed physician. No auto-approvals. No shortcuts.
Licensed Pharmacies
Your cream is compounded by state-licensed, accredited pharmacies following strict quality standards.
24/7 Support
Questions about your treatment? Message our care team anytime — a real person responds within hours.
Compounded medications are prepared by licensed pharmacies but are not FDA-approved finished products. All prescriptions require physician evaluation and approval.
Common questions
SoothRx creams are physician-prescribed compounds containing multiple active pharmaceutical ingredients at prescription-strength concentrations. Unlike OTC products that typically contain a single ingredient (menthol or capsaicin), our creams combine anti-inflammatories, nerve-calming agents, muscle relaxants, and local anesthetics to target pain through multiple pathways simultaneously.
No. Everything is done online. You complete a pain assessment, a licensed physician reviews your information, and if appropriate, prescribes a custom-compounded cream shipped directly to you.
Compounded medications are prepared by state-licensed, accredited pharmacies using FDA-approved pharmaceutical ingredients. While the final compounded product itself is not FDA-approved (this applies to all compounded medications, not just ours), the individual ingredients are well-established and your physician selects the formulation based on your specific needs.
Many patients notice improvement within 1-2 weeks of consistent use. Full effects typically develop over 2-4 weeks as the active ingredients build up in the target area. Your physician may adjust your formulation based on your response.
Yes. There are no long-term contracts. You can pause, adjust, or cancel your subscription at any time through your patient portal.
SoothRx is a cash-pay service. We do not bill insurance directly, but many of our plans are HSA/FSA eligible. Our pricing is typically 50-70% less than what you'd pay for the same compounds through a traditional pain clinic.
Your pain deserves more than another tube of Icy Hot.
Get prescription-strength relief — personalized, doctor-prescribed, and delivered to your door.